Alex Smith was nearly flawless on Monday night, as he had three touchdown passes to lead the 49ers to a 24-3 beating of the Cardinals in an NFC West battle.
Smith had just one incompletion as he went 18-for-19 for 232 yards. He set an NFL record for the most completions with just one incompletion in a single game.
Michael Crabtree caught five passes for 72 yards and two touchdowns while Randy Moss also had a touchdown catch for the 49ers (6-2), who have won their past two and hold a two-game lead for the top spot in the NFC West.
John Skelton, making his second straight start in place of an injured Kevin Kolb, went 32-for-52 for 290 yards with an interception for the Cardinals (4-4), who have dropped four straight since opening the season with four consecutive wins.
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