Michael Vick is in the Eagles’ starting lineup after missing a portion of last week’s loss to the Giants with a bruised right hand.
Vick originally was thought to have a broken hand, but the left-handed passer later was diagnosed with the bruise, and he practiced late in the week.
San Francisco running back Frank Gore is active despite a sprained right ankle, but rookie Kendall Hunter will start.
Neither receiver Braylon Edwards (right knee) nor fullback Moran Norris (left leg) made the trip east for the 49ers. Ted Ginn Jr. and rookie Bruce Miller are starting Sunday.
Eagles defensive end Juqua Parker was inactive with a high ankle sprain. He also missed last week’s game.