According to Phil Wilson’s Colts’ Blog at Indystar.com
Colts coach Jim Caldwell has ruled out MLB Gary Brackett (shoulder) and LB Ernie Sims (knee) for Week 2.
With this injury, second year man Pat Angerer will likely slide over to MLB, with Phillip Wheeler getting the start on the strong side. The other starting outside linebacker, Kavell Conner, is in a boot but expects to play. This is a considerable blow to the Indy defense, which was already going to have a tough time stopping Cleveland’s star RB Peyton Hillis.